Proteoglycans are key functional molecules, consisting of core proteins, found extensively throughout the human body and influential to the maintenance of a balanced and healthy Hair Growth Cycle and general healthy hair growth.
In the hair follicle, they are responsible for regulating the way the hair grows and are key to ensuring that each follicle performs its Hair Growth Cycle correctly. Studies have shown that, when these molecules are depleted or missing, the follicle becomes disrupted in the Hair Growth Cycle and hair thinning or hair loss occurs.
Nourkrin® with Marilex® is a Proteoglycan Replacement Therapy, formulated to normalise the Hair Growth Cycle and promote normal, healthy hair growth.
What is PROTEOGLYCAN REPLACEMENT THERAPY?
It has been clinically documented that proteoglycan levels decline within the hair follicle in age-related or genetic hair loss (Androgenetic Alopecia), post-pregnancy hair loss (Postpartum Effluvium) and whilst experiencing stress-related hair loss (Telogen Effluvium).
The hair follicle relies on a finely tuned dialogue between different compartments in the skin and around the hair follicle, regulated by a delicate balance between various important growth influencers. Proteoglycans’ roles in hair growth control should always be considered when addressing hair growth disorders, no matter their cause or type, as proteoglycans can effectively modulate the growth factors.
The Hair Growth Cycle consists of three phases: the Anagen (growth) phase, the Catagen (transition) phase and the Telogen (resting) phase. The hair follicle returns to begin a new Anagen phase after the hair has been shed in the Telogen phase, thereby maintaining a healthy Hair Growth Cycle and overall healthy hair growth.
Several factors can have a negative impact on a healthy Hair Growth Cycle, disrupting normal hair growth, resulting in a cycle of increased shedding and weak or no re-growth at all. By utilising a Proteoglycan Replacement Therapy, which is rich in specific bioactive proteoglycans, the hair follicles can be induced back into the Anagen phase and begin a new, revitalised Hair Growth Cycle, leading to increased hair growth and hair quality.
There is a well-founded scientific basis for recommending Proteoglycan Replacement Therapy as a primary therapy for subjects suffering from hair loss or hair growth disorders in general.
Nourkrin® with Marilex® is a bioactive proteoglycan formula used as a Proteoglycan Replacement Therapy and is specifically formulated to normalise the Hair Growth Cycle and promote normal, healthy hair growth.
What is PROTEOGLYCAN FOLLICULAR ATROPHY?
Hair loss and hair growth disruptions can be explained by a ‘lower than normal’ concentration of hair growth regulating proteoglycans that causes follicular degradation – this is known as Proteoglycan Follicular Atrophy.
Proteoglycan Follicular Atrophy is today a clinically established pathology and a condition where a wasting away of selective proteoglycans from the dermal papilla, the inner and outer root sheath, occurs, coupled with an ever-decreasing ability of the body to reproduce these in a normal, healthy manner.
Nourkrin®, with the unique, proprietary Marilex®, is a scientifically developed Proteoglycan Replacement Therapy formulated to support normal healthy hair growth by addressing Proteoglycan Follicular Atrophy, which is an underlying cause of almost all cases of hair growth disruptions, no matter the cause or type.
There are many causes for hair loss, e.g., stress, genetics, hormones, childbirth, medicine, health, diabetes, diet, smoking and hairstyling. No matter the cause, the normal, healthy Hair Growth Cycle is always negatively affected.
The Hair Growth Cycle is the all-important mechanism regulating hair growth on the scalp. In order to restore hair and treat hair loss, it is, therefore, necessary to normalise and support the Hair Growth Cycle.
One available and safe method of increasing the concentration of specific hair follicle proteoglycans and normalising the Hair Growth Cycle is to orally administer the specific bioavailable proteoglycans, referred to as Proteoglycan Replacement Therapy.
There is a well-founded scientific and clinical basis for using Proteoglycan Replacement Therapy as primary therapy for subjects suffering hair loss or hair growth disorders, regardless of the cause or type. It has been documented that proteoglycan levels decline within the hair follicle in age-related or genetic hair loss (Androgenetic Alopecia), post-pregnancy hair loss (Postpartum Effluvium) and when experiencing stress-related hair loss (Telogen Effluvium).
Nourkrin® with Marilex® is a bioactive proteoglycan formula used as a Proteoglycan Replacement Therapy and is specifically designed to normalise the Hair Growth Cycle and promote normal, healthy hair growth.
8 out of 10 users saw a significant improvement after taking Nourkrin® – YES, IT WORKS!
What is MARILEX®?
Marilex® and Marilex®-M are the main active components of Nourkrin® Woman and Nourkrin® Man respectively.
Marilex® sets Nourkrin® apart from any other products claiming to contain similar ingredients, because Marilex® is a proprietary ingredient protected by exclusive intellectual property rights for more than 30 years.
Marilex®, as found in Nourkrin® Woman, is rich in specific follicular bioactive proteoglycans obtained from a proprietary enzymatic fractionation of a specific fish extract and contains high proportions of specific papillary proteoglycans which are critical to normal healthy female hair follicle growth and cycling during Telogen Effluvium (hair shedding after giving birth) and Female Pattern Hair Loss (Genetic Hair Loss).
Marilex®-M, as found in Nourkrin® Man, also contains high proportions of these specific papillary proteoglycans plus additional extra proportions of decorin and versican (two integral growth modulatory proteoglycans) that are essential in replenishing the critical papillary proteoglycans that address follicle shrinkage during Male Pattern Hair Loss (genetic hair loss).
Both complexes restore the key proteoglycans in hair follicles that are experiencing Proteoglycan Follicular Atrophy (PFA), which is clinically documented to be a major underlying cause of hair loss in females and males alike, thereby inducing and prolonging the Anagen (growth) phase and ultimately leading to a normalisation of the healthy Hair Growth Cycle.
Marilex® (fractionated fish extract with specific lectican proteoglycans) is made with the highest quality, natural raw materials using an exclusive, protected, enzymatic extraction technology and is accepted by health authorities on all continents of the globe including the FDA, Anvisa, Cofepris and European Food Safety Authority etc.
Each Nourkrin® tablet contains the precise amount of Marilex® that has been used in the clinical studies documenting the efficacy. The other ingredients further influence the Hair Growth Cycle, which is why the bioactive proteoglycan formula of Nourkrin® is not a simple multivitamin, but an effective, scientifically tried and tested Proteoglycan Replacement Therapy for hair growth disruptions in women and men experiencing Proteoglycan Follicular Atrophy.
Is Nourkrin® SAFE AND SIDE EFFECT FREE?
There have been no known side effects since the introduction of Nourkrin® to the UK 30 years ago.
The safety and side-effect-free tolerability of Nourkrin® with Marilex® have been demonstrated in multiple clinical trials featured in leading international medical published journals. The bioactive proteoglycan formula, Nourkrin®, is completely safe and 100% drug-free. It’s entirely based on drug-free ingredients, which are evaluated as safe by food and drug authorities globally. Furthermore, health authorities on all continents accept Marilex®, including the FDA, Anvisa, Cofepris and EFSA (European Food Safety Authority).
Each Nourkrin® tablet contains the exact quantities of Marilex® proven effective in the respective published clinical studies. Additional ingredients further influence the Hair Growth Cycle, and Nourkrin® is, therefore, not a multivitamin but an effective, scientifically proven hair growth product.
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